Clinical Trials - Vitamin D3, Yestimun®

This ultra-strength, vegan formula is geared to maximising immunity at any time of year. We’ve combined vitamin D3 with a scientifically proven beta glucan, botanicals and supportive nutrients to keep you on top of your game. 

What’s An Effective Dose Of Vitamin D?

We’ve provided the highest dose of vitamin D3 possible to positively impact on immunity and optimal health. How have we achieved this?

As we know, adequate vitamin D status is required for calcium absorption and health bones. Vitamin D is also important for a strong immune response. But here’s the thing – there’s a lot more than meets the eye with vitamin D. This vital vitamin is also a hormone and has profound effects on muscle function, heart and brain health and more widely, the inflammatory response. That means when making a call on how much to take, it must be done through the lens of it’s arching effect on multiple areas of body function.

In the UK, the prevalence of low circulating concentrations of vitamin D (circulating 25-hydroxyvitamin D (25(OH)D) <25 nmol/L) often associated with deficiency is around 20% (National Diet and Nutrition Survey). That means 1 in 5 of us could do with a high powdered vitamin D supplement, particularly around the winter months when sunlight exposure is limited. In contrast, the Endocrine Society in the USA suggest that a serum 25(OH)D concentration of more than 75 nmol/L is necessary to maximise the effect of vitamin D on calcium, bone, and muscle metabolism.
Whilst the UK Department of Health recommends 400 i.u vitamin D daily to prevent deficiency, the Endocrine Society suggest 2,000i.u. daily in adults might be better suited to overall health. However, if you’re already tested deficient your doctor may recommend something stronger with some experts recommending around 4,000 i.u. or more daily.

What’s Too High And Unsafe?

Concentrations above 250 nmol/L are considered excessive, with concentrations above 375 nmol l/L being associated with toxicity. Vitamin D treatment appears to be safe at doses of up to 10,000 i.u day, with many in the medical community considering anything over 4,000 i.u. daily as ‘high dose’ and anything above 100,000 i.u. as ‘mega dose’!
At Rock & Roses, we’ve selected the optimal dose of vitamin D3 at 3,000 i.u. daily for the best health possible. Not too high, not too low. Just right.
Vitamin D+ Study 1
Main Finding: Serum 25(OH)D at 100-150 nmol/L is required to achieve the optimal overall health benefits of vitamin D
A 2020 review: Immunologic Effects of Vitamin D on Human Health and Disease
Vitamin D+ Study 2
Main Finding: 20% of the UK population are estimated at having low circulating concentrations of vitamin D (circulating 25-hydroxyvitamin D (25(OH)D) <25 nmol/L).
This finding was cited from the 2013 National Diet and Nutrition Survey (NDNS).

Vitamin D+ Study 3
Main Finding: People taking Yestimun® beta glucans experience fewer common cold episodes!
In representative nutrition studies with more than 100 healthy participants, the prophylactic and therapeutic effects of Yestimun® in cases of uncomplicated colds were investigated.

The Perfect Immunity Partnership: Vitamin D3 and Beta Glucan
Great news! Not only do we provide 3,000 i.u. vitamin D/serving, we’ve added scientifically proven Yestimun® - a highly researched yeast derived beta glucan that targets the gut for improved immune performance! Better still, we’ve rounded this formula with a unique blend of mushroom and ginger botanicals combined with minerals zinc and selenium for the best immune defence possible.